Lipedema & Hormones – How our body reacts

Lipedema affects almost exclusively women – and this draws attention to a fascinating topic: hormones. They accompany us through all phases of life and influence how our bodies change. Many sufferers report that their symptoms worsen during certain hormonal phases. But what's really behind it?

How hormones shape our bodies

Hormones control countless processes in our body—from metabolism and the immune system to fat distribution. The female hormones estrogen and progesterone, in particular, have a direct effect on fat and connective tissue. An imbalance in these hormones can also affect the development and progression of lipedema.


Hormonal changes and lipedema attacks

  • Puberty: During this time, estrogen levels rise sharply. This can lead to increased fat accumulation on the hips, legs, and upper arms—areas typical for lipedema.
  • Pregnancy: The body prepares hormonally for the baby. As a result, many women retain more water and fat, which can exacerbate existing lipedema symptoms.
  • Menopause: When estrogen levels drop, hormonal imbalances are disrupted again. This can intensify swelling, pain, and tightness.
  • Hormonal contraception: Drugs like the pill can also affect fat distribution. It may be beneficial for those affected to consider alternative, non-hormonal contraceptive methods.


Lipedema is a complex disease in which hormones, genetics and lifestyle factors are closely intertwined.

Other possible causes

Besides hormones, other factors also play a role. Many studies show that there is often a genetic predisposition—lipedema often runs in families. Furthermore, disorders in the lymphatic system can impede the removal of fluid, which promotes swelling. Chronic stress can also promote inflammatory processes through the release of the stress hormone cortisol.


Scientifically speaking, lipedema is a chronic, hormone-dependent fat distribution disorder in which inflammatory processes and altered vascular permeability play an important role.

Treatment options

Although lipedema cannot be cured through diet or exercise, the symptoms can be alleviated in a targeted manner.


Conservative therapy: Regular manual lymphatic drainage, compression stockings, and gentle endurance training improve blood circulation and reduce feelings of tension.


Liposuction: In advanced cases of lipedema, surgical removal of the diseased fat cells (liposuction) can significantly and permanently reduce symptoms. Only the diseased fat cells are removed, which is what makes this treatment so effective.

Living with lipedema

Living with lipedema is a daily challenge, but not a dead end. Exercise, a healthy diet, lymphatic therapy, and mental strength help regain well-being. Sharing ideas with other sufferers, self-acceptance, and a positive attitude are just as important as any medical treatment.

Conclusion

Lipedema is a complex condition in which hormones, genetics, and lifestyle factors are closely intertwined. Although research doesn't yet have all the answers, there are now effective ways to alleviate symptoms and regain a sense of self-worth.